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A TAD Skeptic: Is 3D Genome Topology Conserved?

The notion that topologically associating domains (TADs) are highly conserved across species is prevalent in the field of 3D genomics. But what exactly is meant by ‘highly conserved’, and what are the actual comparative data that support this notion? To address these questions, we performed a histor...

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Vydáno v:Trends Genet
Hlavní autoři: Eres, Ittai E., Gilad, Yoav
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8120795/
https://ncbi.nlm.nih.gov/pubmed/33203573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2020.10.009
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