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A TAD Skeptic: Is 3D Genome Topology Conserved?

The notion that topologically associating domains (TADs) are highly conserved across species is prevalent in the field of 3D genomics. But what exactly is meant by ‘highly conserved’, and what are the actual comparative data that support this notion? To address these questions, we performed a histor...

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Publicat a:Trends Genet
Autors principals: Eres, Ittai E., Gilad, Yoav
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8120795/
https://ncbi.nlm.nih.gov/pubmed/33203573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2020.10.009
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