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Nanoscopic quantification of sub-mitochondrial morphology, mitophagy and mitochondrial dynamics in living cells derived from patients with mitochondrial diseases

SLC25A46 mutations have been found to lead to mitochondrial hyper-fusion and reduced mitochondrial respiratory function, which results in optic atrophy, cerebellar atrophy, and other clinical symptoms of mitochondrial disease. However, it is generally believed that mitochondrial fusion is attributab...

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Detalhes bibliográficos
Publicado no:J Nanobiotechnology
Main Authors: Zou, Weiwei, Chen, Qixin, Slone, Jesse, Yang, Li, Lou, Xiaoting, Diao, Jiajie, Huang, Taosheng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8120746/
https://ncbi.nlm.nih.gov/pubmed/33985528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-021-00882-9
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