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Systemic administration of AAV-Slc25a46 mitigates mitochondrial neuropathy in Slc25a46(−/−) mice
Mitochondrial disorders are the result of nuclear and mitochondrial DNA mutations that affect multiple organs, with the central and peripheral nervous system often affected. Currently, there is no cure for mitochondrial disorders. Currently, gene therapy offers a novel approach for treating monogene...
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| Publicado en: | Hum Mol Genet |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7068115/ https://ncbi.nlm.nih.gov/pubmed/31943007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddz277 |
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