MUC3A induces PD-L1 and reduces tyrosine kinase inhibitors effects in EGFR-mutant non-small cell lung cancer

The immune checkpoint ligand programmed death-ligand 1 (PD-L1) and the transmembrane mucin (MUC) 3A are upregulated in non-small cell lung cancer (NSCLC), contributing to the aggressive pathogenesis and poor prognosis. Here, we report that knocking down the oncogenic MUC3A suppresses the PD-L1 expre...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Int J Biol Sci
Main Authors: Luo, Yuan, Ma, Shijing, Sun, Yingming, Peng, Shan, Zeng, Zihang, Han, Linzhi, Li, Shuying, Sun, Wenjie, Xu, Jieyu, Tian, Xiaoli, Wang, Feng, Wu, Qiuji, Xiao, Yu, Zhang, Junhong, Gong, Yan, Xie, Conghua
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2021
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8120466/
https://ncbi.nlm.nih.gov/pubmed/33994852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.57964
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker