Acidic extracellular pH induces autophagy to promote anoikis resistance of hepatocellular carcinoma cells via downregulation of miR-3663-3p

Metastasis is the major reason for poor prognosis and high fatality in hepatocellular carcinoma (HCC). Due to the “Warburg effect”, an acidic tumor microenvironment (TME) exists in solid tumors and plays a critical role in cancer metastasis. Thus, clarifying the mechanism underlying the acidic TME i...

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Publicado en:J Cancer
Main Authors: Wang, Siying, Lv, Yuanyuan, Zhou, Yangyang, Ling, Jing, Wang, Hui, Gu, Dishui, Wang, Cun, Qin, Wenxin, Zheng, Xingling, Jin, Haojie
Formato: Artigo
Idioma:Inglês
Publicado: Ivyspring International Publisher 2021
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Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8120191/
https://ncbi.nlm.nih.gov/pubmed/33995620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.51849
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