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Nanopore direct RNA sequencing detects DUX4-activated repeats and isoforms in human muscle cells
Facioscapulohumeral muscular dystrophy (FSHD) is an inherited muscle disease caused by misexpression of the DUX4 gene in skeletal muscle. DUX4 is a transcription factor, which is normally expressed in the cleavage-stage embryo and regulates gene expression involved in early embryonic development. Re...
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| Publicado no: | Hum Mol Genet |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8120133/ https://ncbi.nlm.nih.gov/pubmed/33693705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddab063 |
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