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Pitfalls of Commonly Used Ischemic and Dementia Models Due to Early Seizure by Carotid Ligation

While the bilateral common carotid artery (CCA) ligation model is widely used in cerebrovascular disease and dementia studies, it can frequently cause seizures. We examined the validity of seizure as an experimental model of ischemia. Eight-week-old male Wistar and Sprague-Dawley (SD) rats were impl...

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Detalhes bibliográficos
Publicado no:Neurol Med Chir (Tokyo)
Main Authors: HIRANO, Tsukasa, MIKAMI, Takeshi, YAMADA, Shoto, NAGAHAMA, Hiroshi, ENATSU, Rei, OOKAWA, Satoshi, AKIYAMA, Yukinori, MIKUNI, Nobuhiro
Formato: Artigo
Idioma:Inglês
Publicado em: The Japan Neurosurgical Society 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8120100/
https://ncbi.nlm.nih.gov/pubmed/33790129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2176/nmc.oa.2020-0365
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