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Pitfalls of Commonly Used Ischemic and Dementia Models Due to Early Seizure by Carotid Ligation

While the bilateral common carotid artery (CCA) ligation model is widely used in cerebrovascular disease and dementia studies, it can frequently cause seizures. We examined the validity of seizure as an experimental model of ischemia. Eight-week-old male Wistar and Sprague-Dawley (SD) rats were impl...

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Bibliographische Detailangaben
Veröffentlicht in:Neurol Med Chir (Tokyo)
Hauptverfasser: HIRANO, Tsukasa, MIKAMI, Takeshi, YAMADA, Shoto, NAGAHAMA, Hiroshi, ENATSU, Rei, OOKAWA, Satoshi, AKIYAMA, Yukinori, MIKUNI, Nobuhiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Japan Neurosurgical Society 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8120100/
https://ncbi.nlm.nih.gov/pubmed/33790129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2176/nmc.oa.2020-0365
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