Disrupting tumour vasculature and recruitment of aPDL1-loaded platelets control tumour metastasis

Although therapies of cancer are advancing, it remains challenging for therapeutics to reach the sites of metastasis, which accounts for majority of cancer associated death. In this study, we have developed a strategy that guides an anti-programmed cell death-ligand 1 (aPDL1) antibody to accumulate...

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Udgivet i:Nat Commun
Main Authors: Li, Hongjun, Wang, Zejun, Chen, Zhaowei, Ci, Tianyuan, Chen, Guojun, Wen, Di, Li, Ruoxin, Wang, Jinqiang, Meng, Huan, Bryan Bell, R., Gu, Zhifeng, Dotti, Gianpietro, Gu, Zhen
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8119987/
https://ncbi.nlm.nih.gov/pubmed/33986264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22674-3
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