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Cryo-shocked cancer cells for targeted drug delivery and vaccination

Live cells have been vastly engineered into drug delivery vehicles to leverage their targeting capability and cargo release behavior. Here, we describe a simple method to obtain therapeutics-containing “dead cells” by shocking live cancer cells in liquid nitrogen to eliminate pathogenicity while pre...

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Bibliografiske detaljer
Udgivet i:Sci Adv
Main Authors: Ci, Tianyuan, Li, Hongjun, Chen, Guojun, Wang, Zejun, Wang, Jinqiang, Abdou, Peter, Tu, Yiming, Dotti, Gianpietro, Gu, Zhen
Format: Artigo
Sprog:Inglês
Udgivet: American Association for the Advancement of Science 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7725453/
https://ncbi.nlm.nih.gov/pubmed/33298439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abc3013
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