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Development of P301S tau seeded organotypic hippocampal slice cultures to study potential therapeutics

Intracellular tau inclusions are a pathological hallmark of Alzheimer's disease, progressive supranuclear palsy, corticobasal degeneration and other sporadic neurodegenerative tauopathies. Recent in vitro and in vivo studies have shown that tau aggregates may spread to neighbouring cells and fu...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: McCarthy, James M., Virdee, Jasmeet, Brown, Jessica, Ursu, Daniel, Ahmed, Zeshan, Cavallini, Annalisa, Nuthall, Hugh N.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8119691/
https://ncbi.nlm.nih.gov/pubmed/33986302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89230-3
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