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Regulation of mammalian 3D genome organization and histone H3K9 dimethylation by H3K9 methyltransferases

Histone H3 lysine 9 dimethylation (H3K9me2) is a highly conserved silencing epigenetic mark. Chromatin marked with H3K9me2 forms large domains in mammalian cells and overlaps well with lamina-associated domains and the B compartment defined by Hi-C. However, the role of H3K9me2 in 3-dimensional (3D)...

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Publicado en:Commun Biol
Autores principales: Fukuda, Kei, Shimura, Chikako, Miura, Hisashi, Tanigawa, Akie, Suzuki, Takehiro, Dohmae, Naoshi, Hiratani, Ichiro, Shinkai, Yoichi
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8119675/
https://ncbi.nlm.nih.gov/pubmed/33986449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-02089-y
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