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PD-L1 tumor-intrinsic signaling and its therapeutic implication in triple-negative breast cancer

Although the immune checkpoint role of programmed death ligand 1 (PD-L1) has been established and targeted in cancer immunotherapy, the tumor-intrinsic role of PD-L1 is less appreciated in tumor biology and therapeutics development, partly because of the incomplete mechanistic understanding. Here we...

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Bibliografiske detaljer
Udgivet i:JCI Insight
Main Authors: Chen, Chunhua, Li, Shiheng, Xue, Junli, Qi, Manlong, Liu, Xin, Huang, Yan, Hu, Jinghua, Dong, Haidong, Ling, Kun
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8119208/
https://ncbi.nlm.nih.gov/pubmed/33884962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.131458
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