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Tau: enabler of diverse brain disorders and target of rapidly evolving therapeutic strategies

Several lines of evidence implicate the protein tau in the pathogenesis of multiple brain disorders, including Alzheimer’s disease, other neurodegenerative conditions, autism, and epilepsy. Tau is abundant in neurons and interacts with microtubules, but its main functions in the brain remain to be d...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Science
Main Authors: Chang, Che-Wei, Shao, Eric, Mucke, Lennart
Format: Artigo
Jezik:Inglês
Izdano: 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8118650/
https://ncbi.nlm.nih.gov/pubmed/33632820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abb8255
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