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Targeting Premature Renal Aging: from Molecular Mechanisms of Cellular Senescence to Senolytic Trials
The biological process of renal aging is characterized by progressive structural and functional deterioration of the kidney leading to end-stage renal disease, requiring renal replacement therapy. Since the discovery of pivotal mechanisms of senescence such as cell cycle arrest, apoptosis inhibition...
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| 出版年: | Front Pharmacol |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Frontiers Media S.A.
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8117359/ https://ncbi.nlm.nih.gov/pubmed/33995028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.630419 |
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