MRI detection of the malignant transformation of stem cells through reporter gene expression driven by a tumor-specific promoter

BACKGROUND: Existing evidence has shown that mesenchymal stem cells (MSCs) can undergo malignant transformation, which is a serious limitation of MSC-based therapies. Therefore, it is necessary to monitor malignant transformation of MSCs via a noninvasive imaging method. Although reporter gene-based...

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Bibliographic Details
Published in:	Stem Cell Res Ther
Main Authors:	Sun, Jun, Huang, Jie, Bao, Guangcheng, Zheng, Helin, Wang, Cui, Wei, Jie, Fu, Yuanqiao, Qiu, Jiawen, Liao, Yifan, Cai, Jinhua
Format:	Artigo
Language:	Inglês
Published:	BioMed Central 2021
Subjects:	Research
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC8117323/ https://ncbi.nlm.nih.gov/pubmed/33980305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02359-w
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MRI detection of the malignant transformation of stem cells through reporter gene expression driven by a tumor-specific promoter

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