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KRAS-driven ROS promote malignant transformation

The mechanism underlying KRAS (Kirsten rat sarcoma viral oncogene homolog)-driven cellular transformation remains unclear because of the complexity of its downstream effectors. Park et al. recently reported that levels of reactive oxygen species (ROS) are increased by KRAS and are responsible for KR...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Suh, Yongjoon, Lee, Su-Jae
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905229/
https://ncbi.nlm.nih.gov/pubmed/27308397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723548.2014.968059
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