Terminal Epitope-Dependent Branch Preference of Siglecs Toward N-Glycans

Siglecs are sialic acid–binding immunoglobulin-like lectins that play vital roles in immune cell signaling. Siglecs help the immune system distinguish between self and nonself through the recognition of glycan ligands. While the primary binding specificities of Siglecs are known to be divergent, the...

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Bibliographische Detailangaben
Veröffentlicht in:Front Mol Biosci
Hauptverfasser: Wang, Shuaishuai, Chen, Congcong, Guan, Minhui, Liu, Ding, Wan, Xiu-Feng, Li, Lei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Molecular Biosciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8116747/
https://ncbi.nlm.nih.gov/pubmed/33996901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2021.645999
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