Novel Small Molecule Glucagon-Like Peptide-1 Receptor Agonist S6 Stimulates Insulin Secretion From Rat Islets

Glucagon-like peptide-1 receptor (GLP-1R) agonist-based therapeutics for type 2 diabetes mellitus have attracted worldwide attention. However, there are challenges in the development of small molecule GLP-1R agonists owing to the complexity of ligand recognition and signal induction mechanisms. Here...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Yang, Xiaohua, Zhang, Min, Lu, Zhihong, Zhi, Linping, Xue, Huan, Liu, Tao, Liu, Mengmeng, Cui, Lijuan, Liu, Zhihong, He, Peifeng, Liu, Yunfeng, Zhang, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8116734/
https://ncbi.nlm.nih.gov/pubmed/33995091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.664802
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