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Beyond cancer cells: Targeting the tumor microenvironment with gene therapy and armed oncolytic virus

Cancer gene therapies are usually designed either to express wild-type copies of tumor suppressor genes or to exploit tumor-associated phenotypic changes to endow selective cytotoxicity. However, these approaches become less relevant to cancers that contain many independent mutations, and the situat...

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Bibliografske podrobnosti
izdano v:Mol Ther
Main Authors: Wan, Peter Kok-Ting, Ryan, Anderson J., Seymour, Leonard W.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Gene & Cell Therapy 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8116634/
https://ncbi.nlm.nih.gov/pubmed/33845199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2021.04.015
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