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“Armed” oncolytic herpes simplex viruses for brain tumor therapy
Genetically engineered, conditionally replicating herpes simplex viruses type 1 (HSV-1) are promising therapeutic agents for brain tumors and other solid cancers. They can replicate in situ, spread and exhibit oncolytic activity via a direct cytocidal effect. One of the advantages of HSV-1 is the ca...
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| Main Author: | |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Landes Bioscience
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2634086/ https://ncbi.nlm.nih.gov/pubmed/19262110 |
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