Cargando...
Revealing the activation mechanism of autoinhibited RalF by integrated simulation and experimental approaches
RalF is an Arf GEF from Legionella pneumophilia, the bacterium that causes severe pneumonia. In its crystal structure, RalF is in the autoinhibited form. A large-scale domain motion is expected to lift the autoinhibition, the mechanism of which is still unknown. Since RalF is activated in the presen...
Gardado en:
| Publicado en: | Sci Rep |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2021
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8115643/ https://ncbi.nlm.nih.gov/pubmed/33980916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89169-5 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|