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Functional display of bioactive peptides on the vGFP scaffold

Grafting bioactive peptides into recipient protein scaffolds can often increase their activities by conferring enhanced stability and cellular longevity. Here, we describe use of vGFP as a novel scaffold to display peptides. vGFP comprises GFP fused to a bound high affinity Enhancer nanobody that po...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Chee, Sharon Min Qi, Wongsantichon, Jantana, Yi, Lau Sze, Sana, Barindra, Frosi, Yuri, Robinson, Robert C., Ghadessy, Farid J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8115314/
https://ncbi.nlm.nih.gov/pubmed/33980885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89421-y
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