NLRP3 inflammasome blockade reduces adipose tissue inflammation and extracellular matrix remodeling

The NLRP3-IL-1β pathway plays an important role in adipose tissue (AT)-induced inflammation and the development of obesity-associated comorbidities. We aimed to determine the impact of NLRP3 on obesity and its associated metabolic alterations as well as its role in adipocyte inflammation and extrace...

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Publicat a:Cell Mol Immunol
Autors principals: Unamuno, Xabier, Gómez-Ambrosi, Javier, Ramírez, Beatriz, Rodríguez, Amaia, Becerril, Sara, Valentí, Víctor, Moncada, Rafael, Silva, Camilo, Salvador, Javier, Frühbeck, Gema, Catalán, Victoria
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8115140/
https://ncbi.nlm.nih.gov/pubmed/31551515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-019-0296-z
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