Increased Tenascin C And Toll-Like Receptor 4 Levels in Visceral Adipose Tissue as a Link between Inflammation and Extracellular Matrix Remodeling in Obesity

CONTEXT: Obesity is associated with an altered inflammatory and extracellular matrix (ECM) profile. Tenascin C (TNC) is an ECM glycoprotein with proinflammatory effects. OBJECTIVE: We aimed to explore the expression levels of TNC in adipose tissue analyzing the contribution of adipocytes and stromov...

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Hauptverfasser: Catalán, Victoria, Gómez-Ambrosi, Javier, Rodríguez, Amaia, Ramírez, Beatriz, Rotellar, Fernando, Valentí, Victor, Silva, Camilo, Gil, María J., Salvador, Javier, Frühbeck, Gema
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2012
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Hot Topics in Translational Endocrinology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462948/
https://ncbi.nlm.nih.gov/pubmed/22851489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2012-1670
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