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Autophagy-dependent removal of α-synuclein: a novel mechanism of GM1 ganglioside neuroprotection against Parkinson’s disease

GM1 ganglioside is particularly abundant in the mammalian central nervous system and has shown beneficial effects on neurodegenerative diseases. In this study, we investigated the therapeutic effect of GM1 ganglioside in experimental models of Parkinson’s disease (PD) in vivo and in vitro. Mice were...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Guo, Yu-Lin, Duan, Wen-Jun, Lu, Dan-Hua, Ma, Xiao-Hui, Li, Xiao-Xiao, Li, Zhao, Bi, Wei, Kurihara, Hiroshi, Liu, Hai-Zhi, Li, Yi-Fang, He, Rong-Rong
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Singapore 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8115090/
https://ncbi.nlm.nih.gov/pubmed/32724177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-020-0454-y
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