C646 inhibits G2/M cell cycle-related proteins and potentiates anti-tumor effects in pancreatic cancer

The activity of histone acetyltransferases (HATs) plays a central role in an epigenetic modification in cooperation with HDACs (histone deacetyl transferases). It is likely that malfunction of this enzymatic machinery controlling epigenetic modification is relevant to carcinogenesis and tumor progre...

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Udgivet i:Sci Rep
Main Authors: Ono, Hiroaki, Kato, Tomotaka, Murase, Yoshiki, Nakamura, Yutaro, Ishikawa, Yoshiya, Watanabe, Shuichi, Akahoshi, Keiichi, Ogura, Toshiro, Ogawa, Kosuke, Ban, Daisuke, Kudo, Atsushi, Akiyama, Yoshimitsu, Tanaka, Shinji, Ito, Hiromichi, Tanabe, Minoru
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8115044/
https://ncbi.nlm.nih.gov/pubmed/33980911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89530-8
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