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Ag(+) Ion Binding to Human Metallothionein-2A Is Cooperative and Domain Specific

Metallothioneins (MTs) constitute a family of cysteine-rich proteins that play key biological roles for a wide range of metal ions, but unlike many other metalloproteins, the structures of apo- and partially metalated MTs are not well understood. Here, we combine nano-electrospray ionization-mass sp...

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Publicado en:Anal Chem
Autores principales: Dong, Shiyu, Shirzadeh, Mehdi, Fan, Liqi, Laganowsky, Arthur, Russell, David H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8114364/
https://ncbi.nlm.nih.gov/pubmed/32515580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.0c00829
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