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Biophysical Compatibility of a Heterotrimeric Tyrosinase-TYRP1-TYRP2 Metalloenzyme Complex

Tyrosinase (TYR) is a copper-containing monooxygenase central to the function of melanocytes. Alterations in its expression or activity contribute to variations in skin, hair and eye color, and underlie a variety of pathogenic pigmentary phenotypes, including several forms of oculocutaneous albinism...

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Udgivet i:Front Pharmacol
Main Authors: Lavinda, Olga, Manga, Prashiela, Orlow, Seth J., Cardozo, Timothy
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8114058/
https://ncbi.nlm.nih.gov/pubmed/33995009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.602206
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