Risk Stratification and Clinical Utility of Polygenic Risk Scores in Ophthalmology

Combining genetic and clinical data into an informative risk prediction profile has been an important ambition of personalized medicine. Single-nucleotide polymorphisms are commonly found throughout the genome and account for the majority of interindividual genetic variation. To date, genome-wide as...

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Bibliografiske detaljer
Udgivet i:Transl Vis Sci Technol
Main Authors: Qassim, Ayub, Souzeau, Emmanuelle, Hollitt, Georgie, Hassall, Mark M., Siggs, Owen M., Craig, Jamie E.
Format: Artigo
Sprog:Inglês
Udgivet: The Association for Research in Vision and Ophthalmology 2021
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8114010/
https://ncbi.nlm.nih.gov/pubmed/34111261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/tvst.10.6.14
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