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Targeting Neutrophil Adhesive Events to Address Vaso-Occlusive Crisis in Sickle Cell Patients

Neutrophils are essential to protect the host against invading pathogens but can promote disease progression in sickle cell disease (SCD) by becoming adherent to inflamed microvascular networks in peripheral tissue throughout the body. During the inflammatory response, leukocytes extravasate from th...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Morikis, Vasilios A., Hernandez, Alfredo A., Magnani, John L., Sperandio, Markus, Simon, Scott I.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8113856/
https://ncbi.nlm.nih.gov/pubmed/33995392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.663886
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