Parvalbumin affects skeletal muscle trophism through modulation of mitochondrial calcium uptake

Parvalbumin (PV) is a cytosolic Ca(2+)-binding protein highly expressed in fast skeletal muscle, contributing to an increased relaxation rate. Moreover, PV is an “atrogene” downregulated in most muscle atrophy conditions. Here, we exploit mice lacking PV to explore the link between the two PV functi...

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Publicat a:Cell Rep
Autors principals: Butera, Gaia, Vecellio Reane, Denis, Canato, Marta, Pietrangelo, Laura, Boncompagni, Simona, Protasi, Feliciano, Rizzuto, Rosario, Reggiani, Carlo, Raffaello, Anna
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8113653/
https://ncbi.nlm.nih.gov/pubmed/33951435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.109087
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