The Mitochondrial Calcium Uniporter controls skeletal muscle trophism in vivo

Muscle atrophy contributes to the poor prognosis of many pathophysiological conditions, but pharmacological therapies are still limited. Muscle activity leads to major swings in mitochondrial [Ca(2+)] which control aerobic metabolism, cell death and survival pathways. We have investigated in vivo th...

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Udgivet i:Cell Rep
Main Authors: Mammucari, Cristina, Gherardi, Gaia, Zamparo, Ilaria, Raffaello, Anna, Boncompagni, Simona, Chemello, Francesco, Cagnin, Stefano, Braga, Alessandra, Zanin, Sofia, Pallafacchina, Giorgia, Zentilin, Lorena, Sandri, Marco, De Stefani, Diego, Protasi, Feliciano, Lanfranchi, Gerolamo, Rizzuto, Rosario
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351162/
https://ncbi.nlm.nih.gov/pubmed/25732818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.01.056
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