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Creating a human-induced pluripotent stem cell-based NKX2.5 reporter gene assay for developmental toxicity testing
To test large numbers of chemicals for developmental toxicity, rapid in vitro tests with standardized readouts for automated data acquisition are needed. However, the most widely used assay, the embryonic stem cell test, relies on the counting of beating embryoid bodies by visual inspection, which i...
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| Publicado no: | Arch Toxicol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8113199/ https://ncbi.nlm.nih.gov/pubmed/33660062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-021-03018-y |
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