A novel human pluripotent stem cell-based assay to predict developmental toxicity

There is a great need for novel in vitro methods to predict human developmental toxicity to comply with the 3R principles and to improve human safety. Human-induced pluripotent stem cells (hiPSC) are ideal for the development of such methods, because they are easy to retrieve by conversion of adult...

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Dettagli Bibliografici
Pubblicato in:Arch Toxicol
Autori principali: Lauschke, Karin, Rosenmai, Anna Kjerstine, Meiser, Ina, Neubauer, Julia Christiane, Schmidt, Katharina, Rasmussen, Mikkel Aabech, Holst, Bjørn, Taxvig, Camilla, Emnéus, Jenny Katarina, Vinggaard, Anne Marie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2020
Soggetti:
In Vitro Systems
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7603451/
https://ncbi.nlm.nih.gov/pubmed/32700165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-020-02856-6
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