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Stereocontrolled Radical Bicyclizations of Oxygenated Precursors Enable Short Syntheses of Oxidized Abietane Diterpenoids

The power of cation-initiated cyclizations of polyenes for the synthesis of polycyclic terpenoids cannot be overstated. However, a major limitation is the intolerance of many relevant reaction conditions toward the inclusion in the substrate of polar functionality, particularly in unprotected form....

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Vydáno v:J Am Chem Soc
Hlavní autoři: Vrubliauskas, Darius, Gross, Benjamin M., Vanderwal, Christopher D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8112877/
https://ncbi.nlm.nih.gov/pubmed/33555176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c13300
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