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Stereocontrolled Radical Bicyclizations of Oxygenated Precursors Enable Short Syntheses of Oxidized Abietane Diterpenoids

The power of cation-initiated cyclizations of polyenes for the synthesis of polycyclic terpenoids cannot be overstated. However, a major limitation is the intolerance of many relevant reaction conditions toward the inclusion in the substrate of polar functionality, particularly in unprotected form....

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Vrubliauskas, Darius, Gross, Benjamin M., Vanderwal, Christopher D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8112877/
https://ncbi.nlm.nih.gov/pubmed/33555176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c13300
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