In vitro reconstitution reveals major differences between human and bacterial cytochrome c synthases

Cytochromes c are ubiquitous heme proteins in mitochondria and bacteria, all possessing a CXXCH (CysXxxXxxCysHis) motif with covalently attached heme. We describe the first in vitro reconstitution of cytochrome c biogenesis using purified mitochondrial (HCCS) and bacterial (CcsBA) cytochrome c synth...

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Veröffentlicht in:eLife
Hauptverfasser: Sutherland, Molly C, Mendez, Deanna L, Babbitt, Shalon E, Tillman, Dustin E, Melnikov, Olga, Tran, Nathan L, Prizant, Noah T, Collier, Andrea L, Kranz, Robert G
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2021
Schlagworte:
Biochemistry and Chemical Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8112865/
https://ncbi.nlm.nih.gov/pubmed/33973521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.64891
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