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Alectinib and lorlatinib function by modulating EMT-related proteins and MMPs in NSCLC metastasis

Most advanced non-small cell lung cancer (NSCLC) patients are accompanied by brain metastasis which is the major cause of increased mortality. The fusion rearrangement of anaplastic lymphoma kinase (ALK) gene is an important feature of brain metastasis in lung cancer. The novel ALK inhibitors alecti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Bosn J Basic Med Sci
Hauptverfasser: Feng, Xu, Xu, En-Shi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8112553/
https://ncbi.nlm.nih.gov/pubmed/33091333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17305/bjbms.2020.5066
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