The potential role of the extracellular matrix in the activity of trabectedin in UPS and L-sarcoma: evidences from a patient‐derived primary culture case series in tridimensional and zebrafish models

BACKGROUND: Soft tissue sarcomas (STS) are a rare group of solid neoplasm including among others liposarcoma, leiomyosarcoma (L-sarcoma) and undifferentiated pleomorphic sarcoma (UPS) entities. The current first-line treatment is represented by anthracycline based- regimens, second-line may include...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Exp Clin Cancer Res
Main Authors: De Vita, Alessandro, Recine, Federica, Miserocchi, Giacomo, Pieri, Federica, Spadazzi, Chiara, Cocchi, Claudia, Vanni, Silvia, Liverani, Chiara, Farnedi, Anna, Fabbri, Francesco, Fausti, Valentina, Casadei, Roberto, Brandolini, Francesca, Ercolani, Giorgio, Cavaliere, Davide, Bongiovanni, Alberto, Riva, Nada, Gurrieri, Lorena, Di Menna, Giandomenico, Calpona, Sebastiano, Debonis, Silvia Angela, Mercatali, Laura, Ibrahim, Toni
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2021
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8111914/
https://ncbi.nlm.nih.gov/pubmed/33975637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-021-01963-1
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