mTOR inhibitor and bone-targeted drugs break the vicious cycle between clear-cell renal carcinoma and osteoclasts in an in vitro co-culture model

The skeleton is one of the most common sites of metastatic spread from advanced clear-cell renal carcinoma (ccRCC). Most of the bone lesions observed in RCC patients are classified as osteolytic, causing severe pain and morbidity due to pathological bone destruction. Nowadays, it is well known that...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Bone Oncol
Päätekijät: Spadazzi, Chiara, Recine, Federica, Mercatali, Laura, Miserocchi, Giacomo, Liverani, Chiara, De Vita, Alessandro, Bongiovanni, Alberto, Fausti, Valentina, Ibrahim, Toni
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2019
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6416775/
https://ncbi.nlm.nih.gov/pubmed/30911462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbo.2019.100227
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