Impact of Gba2 on neuronopathic Gaucher’s disease and α-synuclein accumulation in medaka (Oryzias latipes)

Homozygous mutations in the lysosomal glucocerebrosidase gene, GBA1, cause Gaucher’s disease (GD), while heterozygous mutations in GBA1 are a strong risk factor for Parkinson’s disease (PD), whose pathological hallmark is intraneuronal α-synuclein (asyn) aggregates. We previously reported that gba1...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Brain
Päätekijät: Nakanishi, Etsuro, Uemura, Norihito, Akiyama, Hisako, Kinoshita, Masato, Masanori, Sawamura, Taruno, Yosuke, Yamakado, Hodaka, Matsuzawa, Shu-ichi, Takeda, Shunichi, Hirabayashi, Yoshio, Takahashi, Ryosuke
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2021
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8111776/
https://ncbi.nlm.nih.gov/pubmed/33971917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-021-00790-x
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia