Von Willebrand factor collagen-binding capacity predicts in-hospital mortality in COVID-19 patients: insight from VWF/ADAMTS13 ratio imbalance

BACKGROUND: Microthrombosis is a hallmark of COVID-19. We previously described von willebrand factor (VWF) and their high molecular weight multimers (HMWMs) as potential trigger of microthrombosis. OBJECTIVES: Investigate VWF activity with collagen-binding assay and ADAMTS13 in COVID-19. METHODS AND...

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Udgivet i:Angiogenesis
Main Authors: Philippe, Aurélien, Gendron, Nicolas, Bory, Olivier, Beauvais, Agathe, Mirault, Tristan, Planquette, Benjamin, Sanchez, Olivier, Diehl, Jean-Luc, Chocron, Richard, Smadja, David M.
Format: Artigo
Sprog:Inglês
Udgivet: Springer Netherlands 2021
Fag:
Letter
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8111656/
https://ncbi.nlm.nih.gov/pubmed/33974165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10456-021-09789-3
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