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Detergent-free purification and reconstitution of functional human serotonin transporter (SERT) using diisobutylene maleic acid (DIBMA) copolymer

Structure and function analysis of human membrane proteins in lipid bilayer environments is acutely lacking despite the fundame1ntal cellular importance of these proteins and their dominance of drug targets. An underlying reason is that detailed study usually requires a potentially destabilising det...

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Vydáno v:Biochim Biophys Acta Biomembr
Hlavní autoři: Dilworth, Marvin V., Findlay, Heather E., Booth, Paula J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8111416/
https://ncbi.nlm.nih.gov/pubmed/33744253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2021.183602
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