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Solubilization of Membrane Proteins into Functional Lipid‐Bilayer Nanodiscs Using a Diisobutylene/Maleic Acid Copolymer

Once removed from their natural environment, membrane proteins depend on membrane‐mimetic systems to retain their native structures and functions. To this end, lipid‐bilayer nanodiscs that are bounded by scaffold proteins or amphiphilic polymers such as styrene/maleic acid (SMA) copolymers have been...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Oluwole, Abraham Olusegun, Danielczak, Bartholomäus, Meister, Annette, Babalola, Jonathan Oyebamiji, Vargas, Carolyn, Keller, Sandro
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5299484/
https://ncbi.nlm.nih.gov/pubmed/28079955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201610778
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