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Therapeutic administration of etoposide coincides with reduced systemic HMGB1 levels in macrophage activation syndrome

BACKGROUND: Macrophage activation syndrome (MAS) is a potentially fatal complication of systemic inflammation. HMGB1 is a nuclear protein released extracellularly during proinflammatory lytic cell death or secreted by activated macrophages, NK cells, and additional cell types during infection or ste...

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Pubblicato in:Mol Med
Autori principali: Palmblad, Karin, Schierbeck, Hanna, Sundberg, Erik, Horne, Anna-Carin, Erlandsson Harris, Helena, Henter, Jan-Inge, Andersson, Ulf
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8111379/
https://ncbi.nlm.nih.gov/pubmed/33975537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10020-021-00308-0
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