High Systemic Levels of the Cytokine-Inducing HMGB1 Isoform Secreted in Severe Macrophage Activation Syndrome

Macrophage activation syndrome (MAS) is a potentially fatal complication of systemic inflammation. High mobility group box 1 (HMGB1) is a nuclear protein extensively leaked extracellularly during necrotic cell death or actively secreted by natural killer (NK) cells, macrophages and additional cells...

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Bibliographic Details
Published in:Mol Med
Main Authors: Palmblad, Karin, Schierbeck, Hanna, Sundberg, Erik, Horne, Anna-Carin, Harris, Helena Erlandsson, Henter, Jan-Inge, Antoine, Daniel J, Andersson, Ulf
Format: Artigo
Language:Inglês
Published: ScholarOne 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365070/
https://ncbi.nlm.nih.gov/pubmed/25247290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2014.00183
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