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Spatiotemporal evaluation of the mouse embryonic redox environment and histiotrophic nutrition following treatment with valproic acid and 1,2-dithiole-3-thione during early organogenesis

Redox regulation during metazoan development ensures that coordinated metabolic reprogramming and developmental signaling are orchestrated with high fidelity in the hypoxic embryonic environment. Valproic acid (VPA), an anti-seizure medication, is known to increase markers of oxidation and also incr...

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Detalhes bibliográficos
Publicado no:Reprod Toxicol
Main Authors: Lapehn, Samantha, Piorczynski, Ted B., Hansen, Jason M., Harris, Craig
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8110175/
https://ncbi.nlm.nih.gov/pubmed/33713778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reprotox.2021.03.001
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