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Studies on Fragment-Based Design of Allosteric Inhibitors of Human Factor XIa
Human factor XIa (hFXIa) has emerged as an attractive target for development of new anticoagulants that promise higher level of safety. Different strategies have been adopted so far for the design of anti-hFXIa molecules including competitive and non-competitive inhibition. Of these, allosteric dysf...
Shranjeno v:
| izdano v: | Bioorg Med Chem |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8109618/ https://ncbi.nlm.nih.gov/pubmed/32992249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2020.115762 |
| Oznake: |
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