Mouse Adapted SARS-CoV-2 protects animals from lethal SARS-CoV challenge

The emergence of SARS-CoV-2 has resulted in a worldwide pandemic causing significant damage to public health and the economy. Efforts to understand the mechanisms of COVID-19 disease have been hampered by the lack of robust mouse models. To overcome this barrier, we utilized a reverse genetic system...

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Publicat a:bioRxiv
Autors principals: Muruato, Antonio, Vu, Michelle N., Johnson, Bryan A., Davis-Gardner, Meredith E., Vanderheiden, Abigail, Lokugmage, Kumari, Schindewolf, Craig, Crocquet-Valdes, Patricia A., Langsjoen, Rose M., Plante, Jessica A., Plante, Kenneth S., Weaver, Scott C., Debbink, Kari, Routh, Andrew L., Walker, David, Suthar, Mehul S., Xie, Xuping, Shi, Pei-Yong, Menachery, Vineet D.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory 2021
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8109199/
https://ncbi.nlm.nih.gov/pubmed/33972939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.05.03.442357
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